Dermatomyositis Causes and Symptoms - Overview - The report gives far reaching data on the therapeutics a work in progress for Dermatomyositis, complete with examination by phase of improvement, medication target, instrument of activity (MoA), course of organization (RoA) and atom sort. The report likewise covers the spellbinding pharmacological activity of the therapeutics, its complete. 5. DERMATOMYOSITIS Double peak of onset Average age of onset is 40 In 40% individuals the skin disease is the sole manifestation at onsetMuscle disease may occur- Concurrently, Precede the skin disease, or Follow the skin disease by weeks to years. 6. CLINICAL PRESENTATION Proximal myopathy Skin rash Systemic features- fever, malaise. You just clipped your first slide! Clipping is a handy way to collect important slides you want to go back to later. Now customize the name of a clipboard to store your clips Dermatomyositis is a disorder of the connective-tissue which is defined by swelling of the skin and muscles. - A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 8947b3-MDg2 Juvenile dermatomyositis is a rare, idiopathic inflammatory disease involving the striated muscles and the skin. Similar to adult cases of dermatomyositis, the disease is primarily characterized by progressive, symmetrical, proximal muscle weakness. Dermatologic manifestations may occur with or without muscular disease and include the.
Juvenile dermatomyositis (JDM) can seriously impact your child's daily life, and can also tax the emotional health of your family. Since it's so rare, juvenile dermatomyositis (JDM) can seem scary to family and child—and often it's puzzling to pediatricians, who may not be familiar with the condition Background In 2012, a European initiative called S ingle H ub and A ccess point for pediatric R heumatology in E urope (SHARE) was launched to optimise and disseminate diagnostic and management regimens in Europe for children and young adults with rheumatic diseases. Juvenile dermatomyositis (JDM) is a rare disease within the group of paediatric rheumatic diseases (PRDs) and can lead to. The PowerPoint PPT presentation: Polymyositis, Dermatomyositis, and Autoimmune Necrotizing Myopathy: Clinical Features is the property of its rightful owner. Do you have PowerPoint slides to share? If so, share your PPT presentation slides online with PowerShow.com
Epidemiology. There are two forms, adult and juvenile. Adult dermatomyositis peaks ~ age 50; twice as common in women than men. Juvenile dermatomyositis tends to occur between 5-10 years. Dermatomyositis is the most common form of inflammatory myopathy in children (as opposed to polymyositis and inclusion body myositis World's Best PowerPoint Templates - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. Winner of the Standing Ovation Award for Best PowerPoint Templates from Presentations Magazine. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect DM in children is referred to as Juvenile Dermatomyositis (JDM). The average age of onset of JDM is approximately 7 years old and the female-to-male ratio is about 2:1 [, , ]. The pathogenesis and major clinical and autoantibody phenotypes in children are similar to those in adults Open in figure viewer PowerPoint. Juvenile dermatomyositis (JDM) presents with characteristic rash and symmetric muscle weakness in the extremities. Juvenile polymyositis (JPM) presents with more severe muscle weakness and frequent cardiac involvement, but the rashes of JDM are absent. JPM is more common in black female patients
The estimated annual incidence rate of polymyositis and dermatomyositis varies between 1.9 and 7.7 per million [ 6 - 15 ]. In a 20‐yr study of inflammatory myositis in America from 1963 to 1982, the annual incidence was 5.5 per million [ 6 ]. Interestingly, the incidence was higher (10 per million) in the last decade Damage Extent and Predictors in Adult Juvenile Dermatomyositis and Polymyositis as determined with the myositis damage index. Arthritis & Rheumatism; vol. 60, No. 11, November 2009, pp 3425-3435. DOI 10.1002/art.24904. Annaliese Tisseverasinghe, Sasha Bernatsky, Christian A. Pineau. Cardio PM/DM Dermatomyositis is often associated with a poikiloderma in a photodistribution. Patients often notice an eruption on photoexposed surfaces. The disease is often pruritic, and, sometimes, intense pruritus may disturb sleep patterns. Patients may also complain of a scaly scalp or diffuse hair loss (see the image below)
Juvenile dermatomyositis, the most common inflammatory myopathy of childhood, is a rare systemic autoimmune vasculopathy that is characterised by weakness in proximal muscles and pathognomonic skin rashes. The length of time before the initiation of treatment affects presenting symptoms, laboratory measures, and pathophysiology. It also affects disease outcomes, including the development of. Classification of dermatomyositis (DM) for a definitive diagnosis requires a characteristic rash and other criteria, such as proximal muscle weakness and muscle enzyme level elevation. DM often overlaps with other connective tissue diseases. Calcinosis of soft tissue is a late complication of juvenile DM, but it is uncommon in adult-onset. make powerpoint on juvenile dermatomyositis. Answers. CourseLover (12) Status NEW Posted 01 Jun 2017 06:06 AM My Price 10.00 . It is a systemic disorder that most frequently affects the skin and muscles, but may also affect the joints; the esophagus; the lungs; and, less commonly, the heart dermatomyositis and exercise is well tolerated in patients with juvenile dermatomyositis. Summary There is a strong need to develop new therapies in patients with myositis. To achieve this, more knowledge is needed on the molecular pathogenesis. Targeted therapies using biologics or exercise can be employe
PowerPoint is the world's most popular presentation software which can let you create professional A Juvenile Rheumatoid Arthritis powerpoint presentation easily and in no time. This helps you give your presentation on A Juvenile Rheumatoid Arthritis in a conference, a school lecture, a business proposal, in a webinar and business and professional representations Untreated dermatomyositis can cause some other complications such as Raynaud's phenomenon, cardiovascular and lung disease, as well as cancer and some connective tissue diseases. Raynaud's phenomenon is the medical term for the disease when the fingers, toes, nose, cheeks and ears become pale on low temperatures In dermatomyositis, calcification occurs three times more commonly in juvenile dermatomyositis than in the adult-onset form and may be observed in 40-70 percent of patients [6, 9]. The known risk factors for calcinosis in children include delayed treatment and severe disease . In adults, calcification often presents as firm dermal or. Juvenile Dermatomyositis Immune System Four Keys Feature Of Immune System Chapter 43 Immune System Quizlet, Lymph Nodes Functions In The Immune System Innate Immune System Powerpoint. Green Smoothie Girl 7 Immune Boosters And Viral Killers Do Vacation Weaken Immune System
. Capillaroscopy in children with RP As in adult RP, antinuclear antibodies and capillaroscopy are the strongest predictors in distinguishing between primary RP and RP secondary to CTDs ( 15 - 19 ) (Figure 2 A and B) Juvenile Dermatomyositis • Malaise, easy fatigue, muscle fatigue, fever & rash • Insidious -symmetric progressive proximal muscle weakness & pain • Milestone regression -Inability to hold head upright/maintain a sitting posture/stop walking/unable to dress/climb stairs/Gower
Juvenile dermatomyositis 22. In juvenile dermatomyositis, the skin lesions and weakness are almost always coincidental, but the severity and progression of each varies greatly from patient to patient. Juvenile variant differs from the adult form because of the coexistence of vasculitis, ectopic calcification, and lipodystrophy. 23 Dermatomyositis and polymyositis: clinical presentation. Hospitalization mortality and associated risk factors in patients with. Rituximab for the treatment of refractory adult and juvenile
Slide 1-. Inflammatory Myopathies Susan Wallis, MD. Slide 2-. Idiopathic inflammatory myopathies Polymyositis Dermatomyositis Juvenile dermatomyositis Inclusion body myositis Myositis associated with collagen vascular disease Myositis associated with malignancy Objective. There are a number of different approaches to the initial treatment of juvenile dermatomyositis (JDM). We assessed the therapeutic approaches of North American pediatric rheumatologists to inform future studies of therapy in JDM. Methods. A survey describing clinical cases of JDM was sent to pediatric rheumatologists. The cases described children with varying severity of typical. Idiopathic Inflammatory Myopathies Epidemiology Annual incidence - 1:100,000 Incidence of individual myositides has been limited by the different diagnostic criteria employed in various epidemiological studies IBM is the most common myopathy after age 50 with prevalence of 3.5/100,000 cases Disease of adults (except for Juvenile DM) Women are more commonly affected Genetic predisposition. INTRODUCTION. Juvenile dermatomyositis (DM), the most common pediatric inflammatory myopathy, is a small‐vessel systemic vasculopathy in which children present with symmetric proximal muscle weakness and a characteristic rash (1, 2).As many as 30% of patients with juvenile DM develop the painful complication of pathologic soft tissue calcifications ()
Patients with juvenile DM were recruited from Great Ormond Street Hospital NHS Foundation Trust through the Juvenile Dermatomyositis Cohort and Biomarker Study (3, 24) between September 2015 and January 2018 and were studied cross-sectionally. A subgroup of the patients studied cross-sectionally were also evaluated prospectively Finally, people with dermatomyositis particularly in juvenile cases, can develop calcinosis. These are calcium deposits that form under the skin and in muscles and tendons. We also see these in scleroderma, lupus, and mixed connective tissue disease. Lungs. Myositis can cause a host of different pulmonary manifestations Dermatomyositis is an autoimmune condition that causes skin changes and muscle weakness. Symptoms can include a red skin rash around the eyelids, red bumps around the joints, and muscle weakness in the arms and legs. Dermatomyositis is most common in adults between ages 40 and 60, or in children between ages 5 and 15 Juvenile Dermatomyositis. Juvenile dermatomyositis (JDMS) manifests as a chronic autoimmune inflammatory disorder of skin and muscle typically characterized by a rash, proximal muscle weakness, and elevation of muscle enzymes. The clinical hallmarks are listed in Table 10-12. If the rash is absent, the term polymyositis is applied SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), COVID-19 (Coronavirus Disease 2019), JDM (Juvenile Dermatomyositis), AST (Aspartate transaminase), ALT (Alanine aminotransferase), LDH (Lactate dehydrogenase), pro-BNP (pro-brain natriuretic peptide), CPK (Creatine phosphokinase), RT-PCR (real-time reverse transcription polymerase.
Juvenile dermatomyositis (JDM) is a chronic inflammatory disease characterized by typical skin lesions and muscle weakness, which occurs in children and adolescents younger than 16 years.1 JDM is classified into 3 clinical types according to the posttreatment course: (1) monocyclic, in which there is one episode with permanent remission within 2 years after diagnosis; (2) polycyclic, with. Juvenile dermatomyositis (JDM) is a rare autoimmune disease and is the most common subset, representing up to 85% of idiopathic inflammatory myopathy (IIM) in children. It is a systemic vasculopathy characterized by symmetrical proximal muscle weakness, raised serum concentrations of muscle enzymes, and pathognomonic skin rashes that include. INTRODUCTION. Dermatomyositis (DM) and polymyositis (PM) are immune-mediated myopathies, characterized by the shared features of proximal skeletal muscle weakness and evidence of muscle inflammation [ 1-4 ]. DM, unlike PM, is associated with a variety of characteristic skin manifestations Objective To describe the methodology used to develop new classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIMs) and their major subgroups. Methods An international, multidisciplinary group of myositis experts produced a set of 93 potentially relevant variables to be tested for inclusion in the criteria. Rheumatology, dermatology, neurology and paediatric.
INTRODUCTION — Dermatomyositis (DM) and polymyositis (PM) are idiopathic inflammatory myopathies, characterized by the shared features of proximal skeletal muscle weakness and evidence of muscle inflammation .DM, unlike PM, is associated with a variety of characteristic skin manifestations. A form of DM, termed amyopathic DM (ADM, also known as dermatomyositis sine myositis), is a. Juvenile dermatomyositis (JDM) is an autoimmune disease causing vasculitis that manifests itself in children; it is the pediatric counterpart of dermatomyositis. In JDM, the body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis Na SJ, Kim SM, Sunwoo IN, Choi YC. Clinical characteristics and outcomes of juvenile and adult dermatomyositis. J Korean Med Sci. 2009 Aug. 24(4):715-21. . . Cheeti A, Brent LH.
Thomas C. King MD, PhD, in Elsevier's Integrated Pathology, 2007 Myositis. Myositis is an inflammatory condition of muscle that can develop in the setting of collagen vascular disease or as a paraneoplastic syndrome. Patients with dermatomyositis have a combination of skin lesions and inflammatory myopathy. Muscle biopsy can be helpful in clarifying the etiology of myositis by virtue of the. Juvenile dermatomyositis (JDM) is a rare systemic autoimmune vasculopathy characterised by weakness in proximal muscles and pathognomonic skin rashes.1 Clinically, some patients are refractory to any available treatments or became steroids dependent.2 The adverse reactions of long-term use of steroids are severe; therefore, more effective and safer medications are urgently needed PowerPoint is the world's most popular presentation software which can let you create professional Juvenile Idiopathic Arthritis powerpoint presentation easily and in no time. This helps you give your presentation on Juvenile Idiopathic Arthritis in a conference, a school lecture, a business proposal, in a webinar and business and professional representations A 17-year-oldman, who had received a diagnosis of juvenile polymyositis (PM) at theage of 1 year, developed recurrent spontaneous pneumothoraces andunderwent surgical treatment by means of video-assisted thoracicsurgery. Intraoperative observation and microscopic studiesdemonstrated numerous bleb-like lesions below the visceral pleura. Toour knowledge, this is the first article that describes.
Idiopathic inflammatory myopathy is a group of disorders characterized by inflammation of the muscles used for movement (skeletal muscles). Idiopathic inflammatory myopathy usually appears in adults between ages 40 and 60 or in children between ages 5 and 15, though it can occur at any age.The primary symptom of idiopathic inflammatory myopathy is muscle weakness, which develops gradually over. Dermatomyositis (dur-muh-toe-my-uh-SY-tis) is an uncommon inflammatory disease marked by muscle weakness and a distinctive skin rash. DM is a connective-tissue disease related to polymyositis (PM) that is characterized by inflammation of the muscles and the skin. While DM most frequently affects the skin and muscles, it is a systemic disorder. The diagnosis of juvenile dermatomyositis was established. Treatment with oral ibuprofen [days 10-17 after admission to the hospital; 24 mg/kg/day (7) ] did not improve the child's status. Prednisone therapy [1.2 mg/kg/day (8-10) ] was initiated, leading to a rapid clinical improvement of muscular and cutaneous symptoms with a concomitant.
The idiopathic inflammatory myopathies are uncommon childhood conditions that present with proximal muscle weakness and characteristic cutaneous manifestations. Juvenile dermatomyositis (JDM) is the most common subtype, comprising 80% to 85% of cases.1 The overall prognosis of JDM has improved considerably over the last few decades because of more aggressive use of corticosteroids and other. . Methods Twenty patients with DM (n=9) or PM (n=11) with refractory disease were enrolled in a randomised treatment delayed-start trial to receive either immediate active treatment with intravenous abatacept or a 3 month delayed-start Antimelanoma differentiation-associated gene 5 (MDA5) dermatomyositis is a recently described disease entity that presents with distinct mucocutaneous and systemic features.1 In this case report, we describe a patient with anti-MDA5 dermatomyositis who presented with interstitial lung disease (ILD), classic cutaneous findings, and acute encephalopathy
Juvenile Arthritis . Affects nearly 300,000 American kids* Arthritis in children is known as juvenile arthritis (JA). These kids have immune systems that, for unknown reasons, attack their self-tissue in and around their joints. The most common type of JA is juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthriti Juvenile Dermatomyositis. Mixed / Undifferentiated connective tissue disease. Vasculitis. Systemic (large, medium, and small-vessel) Localized (cutaneous PAN, CNS vasculitis) Autoinflammatory PowerPoint Presentation Last modified by: Steve Jansky. Dyspnea and Rash PowerPoint Presentation. DOWNLOAD POWERPOINT PRESENTATION. Dyspnea, Rash, Idiopathic, Inflammatory Myopathies, Polymyositis, Dermatomyositis, Juvenile dermatomyositis, Inclusion body myositis, Myositis associated with collagen vascular disease, Myositis associated with malignancy, anti-synthetase syndrome. Published on.
Juvenile dermatomyositis (JDM) is the most common in-flammatory myopathy of childhood and a major cause of morbidity and mortality among patients with pediatric rheumatic diseases . The management of JDM is highly variable internationally [2, 3]. Few controlled trials have been performed on the treatment of JDM, e.g. on metho Koebner phenomenon is an isomorphic response seen in a variety of dermatoses such as psoriasis. Its key feature is the appearance of a new dermatosis in previously unaffected areas following trauma. An 8-year-old girl presented with several months history of a worsening rash on her hands and face, pruritus, and proximal muscle weakness. At age 4, a diagnosis of juvenile dermatomyositis was.
Objective. To evaluate the safety and efficacy of rituximab (RTX) in juvenile dermatomyositis (JDM) in off-trial patients. Methods. We conducted a multicenter prospective study of patients with JDM included in the French Autoimmunity and Rituximab (AIR) registry. Results. Nine patients with severe JDM were studied. The main indication for RTX treatment was severe and/or refractory muscle. Juvenile dermatomyositis is a subset of DM occurring in patient 18 years old or less. 8 Polymyositis is a disease state that shares similar pathophysiology with DM. Polymyositis is an idiopathic inflammatory myopathy; however, it lacks skin involvement that is seen in DM. 5 Polymyositis is defined as a subacute myopathy, which takes more than 4.
In both adult and juvenile dermatomyositis, type I interferon-related cytokines and chemokines are upregulated in the muscle and blood of patients who have active disease 88,89,90,91,92,96,97,98. Juvenile dermatomyositis (JDMS) is a relatively rare disease characterised by vasculopathy.1-4 Involvement of the gastrointestinal tract may occur in some subjects and is often life threatening. We describe here a case of fatal JDMS with gastrointestinal perforation. Immunohistochemical examination by antibody against factor VIII seems to be useful for evaluating the pathological basis of. Idiopathic inflammatory myopathies (IIM) include the main subgroups polymyositis (PM), dermatomyositis (DM), inclusion body myositis (IBM) and juvenile DM (JDM). The mentioned subgroups are characterised by inflammation of skeletal muscles leading to muscle weakness and other organs can also be affected as well. Even though clinically significant heart involvement is uncommon, heart disease is. Read chapter 149 of Comprehensive Pediatric Hospital Medicine, 2e online now, exclusively on AccessPediatrics. AccessPediatrics is a subscription-based resource from McGraw Hill that features trusted medical content from the best minds in medicine
Dermatomyositis (DM) is a multifactorial chronic autoimmune disorder with characteristic skin changes and involvement of different organ systems, including the muscles, blood vessels, joints, esophagus, and lungs. In terms of epidemiology, DM affects both children and adults. It is most often observed beyond the age of 40, but there is also a peak of incidence between 5 and 12 years of age . V. et al. Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: a randomized, placebo-phase trial. Arthritis Rheum. 65 , 314-324 (2013)
Ambler GR, Chaitow J, Rogers M, McDonald DW, Ouvrier RA. Rapid improvement of calcinosis in juvenile dermatomyositis with alendronate therapy. J Rheumatol. 2005 Sep. 32(9):1837-9. . Slimani S, Abdessemed A, Haddouche A, Ladjouze-Rezig A. Complete resolution of universal calcinosis in a patient with juvenile dermatomyositis using pamidronate Dermatomyositis is one of the idiopathic inflammatory myopathies. It is characterized clinically by progressive symmetrical proximal muscle weakness and a characteristic rash. There are patients with rash who have little or no muscle disease. Although the process primarily attacks the skin and the muscles, it is a systemic disease with frequent manifestations in the gastrointestinal tract and. Batten disease is a rare group of nervous system disorders called neuronal ceroid lipofuscinosis (NCLs) that get worse over time. It usually starts in childhood, between the ages of 5 and 10.
The idiopathic inflammatory myopathies are a group of conditions characterised by inflammation of muscles (myositis) and other body systems. The diagnosis can be challenging because of the many potential clinical features and extra-muscular manifestations, which may be seemingly unrelated. An accurate diagnosis requires up-to-date understanding of the clinical manifestations, different. The inflammatory myopathies, commonly described as idiopathic, are the largest group of acquired and potentially treatable myopathies. On the basis of unique clinical, histopathological, immunological, and demographic features, they can be differentiated into three major and distinct subsets: dermatomyositis, polymyositis, and inclusion-body myositis We report a case of juvenile dermatomyositis (JDM) with cytomegalovirus (CMV) colitis which was further complicated with perforation. The patient, a 6-year-old girl, was diagnosed with JDM 1 month prior to the current presentation. After 2 weeks of optimising her treatment with steroid, intravenous Ig and methotrexate, she was readmitted with diffuse abdominal pain Amyopathic juvenile dermatomyositis is a rare variant of JDM, and such a diagnosis was made after the exclusion of other immune-mediated diseases (eg, systemic lupus erythematosus, sarcoidosis, vasculitis, etc), as the corresponding diagnostic criteria were not fulfilled, and the exclusion of diseases due to infections and drugs, based on the. Juvenile systemic lupus erythematosus (SLE) with or without antiphospholipid syndrome, juvenile dermatomyositis (JDM), sclerodermiform syndromes, mixed connective tissue disease (MCTD), and Sjögren syndrome are the disorders that affect children most frequently. Their clinical manifestation is diverse, and potentially all organs can be affected
Juvenile dermatomyositis is an autoimmune connective tissue disease occurring in children less than 16 years old. It is part of a heterogeneous group of muscle diseases called idiopathic Iiflammatory myopathies. It had previously been reported in black Africans resident in UK. However, there is no documented case reported from Africa. The index sign of heliotrope rashes is often difficult to. Overview. Dermatomyositis is a rare inflammatory disease. Common symptoms of dermatomyositis include a distinctive skin rash, muscle weakness, and inflammatory myopathy, or inflamed muscles The presence of anti-TIF1-γ antibodies is associated with increased risk of malignancy in dermatomyositis and should prompt the clinician to initiate age-appropriate cancer screenings.3 4 A significant proportion of anti-TIF1-γ positive adult patients with dermatomyositis have no detectable malignancy at the time of the disease onset, thus continued cancer surveillance and reassessment is. JUVENILE RHEUMATOID. ARTHRITIS Pragna Vanapala SGU SOM September 4th, 2015. Background Information Also known as juvenile idiopathic arthritis Most common rheumatic disease in children and one of the more common. chronic illnesses of childhood JRA/JIA a group of disorders that all share clinical manifestations of arthritis Etiology and pathogenesis largely unknown, and genetic component is.
Familial Mediterranean Fever (FMF) is a rare hereditary auto-inflammatory disease that can be exceptionally associated with many other dys-immune disorders; the most reported associations were with systemic vasculitis, spondyloarthropathies, inflammatory bowel diseases, systemic lupus erythematous, multiple sclerosis, and juvenile chronic arthritis Download powerpoint; Figure 2. mainly systemic sclerosis and dermatomyositis.2 Although this condition is more frequent in juvenile dermatomyositis, it can also occur in adults.2 Its underlying mechanisms are not fully understood but these lesions,. Editor-In-Chief: C. Michael Gibson, M.S., M.D.; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D. Overview. The exact pathogenesis of polymyositis and dermatomyositis is not fully understood. However, it is understood that polymyositis and dermatomyositis are the result of autoimmune attack but triggering factors are not well-known. Polymyositis is caused by inflammation and degeneration of. ICD-10-CM Diagnosis Code M33.01. Juvenile dermatomyositis with respiratory involvement. 2016 2017 2018 - Revised Code 2019 2020 2021 Billable/Specific Code. specified organ involvement NEC M33.09. ICD-10-CM Diagnosis Code M33.09. Juvenile dermatomyositis with other organ involvement Methods. IIM between 2004 to 2015 were identified using the Korean National Health Insurance Service medical claim database. The case definition required more than one visit based on diagnostic codes including juvenile dermatomyositis (JDM), dermatomyositis (DM), or polymyositis (PM) and registration in the Individual Copayment Beneficiaries Program (ICBP) for rare and intractable diseases
Rheumatoid Arthritis (RA) is a chronic, inflammatory autoimmune disease that can overlap with Myositis. The disease involves the lining of the joints, causing the joints to become swollen and inflamed. RA is not a rare disease. Approximately 41 people out of every 100,000 are diagnosed with this disease. As with most autoimmune diseases, there. The most common symptoms of all types of juvenile rheumatoid arthritis-- also called JRA or juvenile idiopathic arthritis (JIA) -- are persistent joint swelling, pain, and stiffness that typically.