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Superficial morphea pathology

Morphea limited to the superficial reticular dermis: an

Morphea (localized scleroderma) is a disease of unknown etiology, presenting as circumscribed areas of indurated skin. Histologically, most cases of morphea feature thickened collagen bundles in the deep reticular dermis, sometimes also extending into the superficial dermis or into the subcutis Abstract The superficial variant of morphea is a recently described entity that differs in its clinical and histologic presentation from classic morphea The superficial variant of morphea is a recently described entity that differs in its clinical and histologic presentation from classic morphea Superficial morphea (SM) is an uncommon entity that is characterized by localized deposition of extra collagen in the papillary and upper reticular dermis. Although there are few reports describing the clinical and pathological features of this variant, there is a debate about its relation to other atrophodermic diseases [ Superficial morphea, a newly described variant of morphea, manifests clinically with hypopigmented or hyperpigmented patches that lack induration. The lesions show on biopsy dermal sclerosis in the superficial to mid‐reticular dermis. So far, all cases reported in the literature were skin limited

Superficial morphea - PubMe

The major defining characteristics of superficial morphea include bilateral atrophic plaques or patches in the intertriginous areas and/or trunk and histologically thickened collagen in the superficial dermis with presence of elastic fibers. Superficial (dermal) atrophy is seen as shiny skin, often with visible blood vessels. Deeper atrophy affecting fat, muscle or bone presents as concave indentations or discrepancies of limb circumference. Morphoea classically passes through each of these morphological stages, this does not always occur. Deep tissue involvement in morphoe Etiology. Atrophic, hypopigmented patches or plaques, usually affecting the upper trunk, neck, flexor wrist or anogenital region. In girls, may start at an early age with hemorrhagic perianal lesions; associated with constipation; may be mistaken for sexual abuse. LS may co-exist with lichen planus and morphea or resemble lichen planus ( Case. LS. Morphea and itssubtypes canexist as a spectrum within LS; however, we were not inclined to di-agnose LS because of the distribution of the lesions and the clinical findings. Similarly, these patients could have concomitant deeper morphea with superficial morphea. However, in each case, the biopsy site was an active and representative lesion Morphea (localized scleroderma of the skin) is a connective tissue disease of unknown origin that afflicts women three times more often than men. 1 The classic lesion is an indurated plaque, often described as having an active, violaceous border with a yellow to white center

Superficial morphea

Morphea profunda is a type of panniculitis. It is also known as scleroderma panniculitis There is a superficial and deep perivascular inflammatory infiltrate composed of lymphocytes, plasma cells, and rarely eosinophils, more marked in morphea than in systemic scleroderma. A frequent finding is an infiltrate of plasma cells at the dermal-subcutaneous junction Morphea (localized scleroderma) is a disease of unknown etiology, presenting as circumscribed areas of indurated skin. Histologically, most cases of morphea feature thickened collagen bundles in the deep reticular dermis, sometimes also extending into the superficial dermis or into the subcutis. We present six cases of morphea in which typical histologic features were restricted to the. In the superficial variant, plaque-type lesions are characterized as circumscribed, indurated plaques that range from 1 cm to more than 20 cm in diameter. These lesions are relatively superficial,.. The major defining characteristics of superficial morphea include bilateral atrophic plaques or patches in the intertriginous areas and/or trunk and histologically thickened collagen in the superficial dermis with presence of elastic fibers. 2 Differential diagnosis includes classic morphea, lichen sclerosus (LS), and idiopathic atrophoderma of Pasini and Pierini (IAPP)

Background: Scleroderma/morphea is characterized by expansion of the dermis with thickened collagen bundles and loss of CD34 + dermal dendrocytes. Variable elastic fiber changes have been described, but to our knowledge, no systematic study of the elastic fiber pattern correlated with CD34 expression has been reported lupus erythematosus with superficial morphea, diagnoses that are supported by histopathologic features and laboratory studies Localized scleroderma, morphea. Clinical signs. localized scleroderma — morphea — roundish lesions, usually on the trunk. linear scleroderma: linear scars of the head and extremities. red-brown borders of the lesions in acute disease, later stiffening and sclerosis, hypo- or hyperpigmentation

Basal Cell Carcinoma - Dermatopathology - Mussen Healthcare

Superficial morphea, a rare variant of morphea, is characterized by hypopigmented to hyperpigmented skin lesions located predominantly in a symmetric fashion at intertriginous sites. These patches.. Morphea is an autoimmune skin disease with protean clinical manifestations. Histologic features are similarly variable, and skin biopsies may be nondiagnostic. A single-institution retrospective cohort study was conducted Morphea/Scleroderma Sudeep Gaudi, MD Drazen M. Jukic, MD, PhD Key Facts Terminology Scleroderma limited to skin, subcutaneous tissue, and underlying muscle and bone Etiology/Pathogenesis Environmental trigger in a genetically predisposed individual lends to launch of cytokine-driven profibrotic cascade following microvascular injury Clinical Issues Classified into 5 subtypes according to. Morphea, also referred to as LS, is a fibrotic autoimmune disease of the skin and underlying tissues that is equally frequent in children and adults. 1, 2 The clinical subtypes (superficial circumscribed morphea, generalized morphea, deep morphea, and linear and mixed scleroderma) 3 share the same histologic features as systemic scleroderma. Synopsis. square specimen / cookie cutter sign. thickened dermis. absence of adnexae. swollen collagen. dermal fibrosis. high eccrine glands. line sign

Cutaneous findings were significant for superficial morphea and lichen sclerosus without evidence of eosinophilia, consistent with a paraneoplastic scleroderma-like eruption. This case report highlights an interesting and important association between aplastic anemia and sclerosing skin disorders Answer. Morpheaform basal cell carcinoma is an uncommon variant in which tumor cells induce a proliferation of fibroblasts within the dermis and an increased collagen deposition (sclerosis) that. Atrophoderma of Pasini and Pierini usually first appears in adolescence or early adulthood (second and third decade). Onset in infancy, childhood, and late adult-life has been reported, as has congenital presentation. There is a strong female predominance (2-6:1) and most reports have been in Caucasians. Familial cases have been described

Superficial Morphea: Clinicopathological Characteristics

Superficial morphea: 20‐year follow up in a patient with

Basal cell carcinoma should be subdivided into different types, i.e. infiltrative, sclerosing or morpheaform, or micronodular as the aggressive subtypes and superficial and nodular as the circumscribed or non-aggressive subtypes. This will lead to better care for any individual's specific basal cell carcinoma superficial morphea-associated fibrous arthropathy by showing absent or moderate thickening of synovium with mild enhancement after gadolinium infusion and no bone erosion or synovial effusion. A synovial pathology study evidenced that this arthropathy resulted from synovial fibrosis with minima

Jablonska, S, Blaszczyk, M. Is superficial morphea synonymous with atrophoderma Pasini-Pierini?. J Amer Acad Dermatol. vol. 50. 2004. pp. 979-80. (This is an opinion piece that asks the readers to abandon the designation APP and replace it with superficial morphea. The readers need to decide whether the argument is convincing. However, lesions of morphea with superficial pallor never demonstrate a superficial lymphoid band, vacuolar interface dermatitis, or follicular plugging. Deep dermal sclerosis is always present. The sclerotic process in linear scleroderma and deep morphea (morphea profunda) extends into the subcutaneous fat and possibly fascia and bone Morphea is a type of Localized Scleroderma of unknown cause. There are several different types of Morphea, which include Circumscribed Morphea, Generalized Morphea, and Superficial Morphea. The healthcare provider can assist in identifying the type of Morphea an individual is diagnosed with Ryanne Brown, M.D., M.B.A., is a Clinical Assistant Professor of Pathology and (by courtesy) Dermatology. She completed her residency training in Anatomic and Clinical Pathology followed by Surgical Pathology and Dermatopathology fellowships at Stanford

• Circumscribed (plaque) morphea is the most common variant in adults, presenting with ≤3 discrete indurated plaques; the latter favor the trunk and tend to develop in areas of pressure (e.g. hips, waist, and bra line in women); superficial and deep variants (morphea profunda) exist Morphea is a rare skin condition characterized by small red or purple patches that develop firm white or ivory centers. The affected skin becomes tight and less flexible. Morphea (mor-FEE-uh) is a rare condition that causes painless, discolored patches on your skin. Typically, the skin changes appear on the belly, chest or back Common variant is the superficial type (Fig. 18C), which often appears as a thin plaque. Morphea-form may present as hypopigmented, depressed firm plaque (Fig. 18D). Other variants include cystic type, fibroepithelioma of Pinkus type, and pigmented basal cell carcinoma (Fig. 18E), which can mimic melanocytic nevi or melanomas The diagnosis of superficial spreading in situ melanoma was made. Excisional margins were negative. Histopathological examination of the punch biopsy performed on the erythematous ring-shaped patch showed diffuse sclerosis in the dermis (Fig. 2A and B) which was regarded as consistent with the clinical diagnosis of morphea Morphea is a cutaneous disorder characterized by excessive collagen deposition. While in almost all cases the sclerosing process exclusively affects the skin, there are anecdotal cases in which associated mucosal involvement has been described. In 1999 McNiff et al. (1) described the first cases of superficial morphea, presenting as pigmented mucosal lesions with minimal cutaneous induration

Superficial morphea: A rare condition and report of three

  1. The main types of basal cell cancer differ from one another in appearance, structure, and degree of aggressiveness. People who are diagnosed with basal cell cancer of the skin are given treatments that correspond to the specific type found (superficial, infiltrative, or nodular). Each of the three types of basal cell carcinoma encompasses several subtypes of the condition
  2. Pansclerotic morphea (PSM) is a rare skin disease characterized by progressive stiffening of the skin with or without the typical superficial skin changes usually seen in morphea (localized scleroderma). Standard therapy, consisting of a combination of systemic glucocorticoids and methotrexate or mycophenolate mofetil, does rarely stop disease progression, which may lead to severe cutaneous.
  3. Lichen sclerosus has a vacuolar interface pattern and dermal sclerosis. Established lesions show hyperkeratosis, follicular plugging, thinning of the epidermis, and vacuolar alteration of the basal layer. There is a broad zone of subepidermal edema with homogenization of collagen and poor staining in hematoxylin and eosin preparations
  4. The epidermis was slightly atrophic. Within four months, the cutaneous lesions disappeared spontaneously. Self-involuting atrophoderma of the lateral-upper arm (SALA), first described by Inazumi et al., in 1997, may represent, as in this case, a benign superficial form of morphea
  5. Morphea is a disease of skin the underlying connective tissue. Several variants have been described, as discussed below. Systemic scleroderma may affect multiple organ systems and is usually classified under autoimmune diseases. Occasionally, morphea and scleroderma may occur in the same patient. In these cases, morphea arises first followed by.
  6. Morphea-like tattoo reaction. Mahalingam M, Kim E, Bhawan J. Am J Dermatopathol 2002; 24:392-395. An unusual tattoo reaction is described that mimicked morphea histologically. A 25-year-old woman presented with a pruritic, inflamed, and indurated area over a 1-year-old red, green, purple, and black tattoo on the left lateral ankle

Morphea may present at any age. In children, the linear subtype predominates while in adults' plaque and generalized subtypes are most common. Morphea occurs more frequently in women, especially in adults where female predominance is marked (5:1). Morphea is not the same as scleroderma (systemic sclerosis), and it does not become scleroderma After 3 to 6 months, BR was seen in 93% of patients (41 of 44) with deep morphea and 77% of patients (23 of 30) with superficial morphea. Compared with patients with superficial morphea, those with deep morphea had an 11.2-fold greater likelihood of BR, although the 95% CI (1.77-219.00) suggested significant imprecision Read Perineural inflammation in morphea (localized scleroderma): systematic characterization of a poorly recognized but potentially useful histopathological feature, Journal of Cutaneous Pathology on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips Pathology - S2B4 - Skin 3; Pathology - S2B4 - Skin 3. by nwess459, Apr. 2007. Subjects: pathologys2b4 . Click to Rate Hated It Superficial BCC 4. Morphea-like BCC 5. Pigmented BCC (may resemble melanoma) What are the most common sites of Basal Cell Carcinoma?. Morphea in Saudi Arabia, a Clinical Study of 64 Patients. Ahmed Alhumidi 1, Shaikhah Alanazi 2* Mona Alfaraidi 3, Najd Alshamlan 4 , Acya Alanazi 5 and Raghad Khalil 6. 1 Department of Pathology, College of medicine, King Saud University, Riyadh, Saudi Arabia. 2 Department of Dermatology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia

Panniculitis - Libre Pathology

Morphoea DermNet N

Scalp morphea presents as a scarring alopecia in en coup du sabre pattern. We report an unusual presentation of a round hairless patch of morphea on the occipital scalp present for 15 years. The scalp lesion aligned with 2 other hyperpig-mented lesions of biopsy-proven morphea in the lower back. Pathology of horizontal sections from the scalp. Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer. It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it. It may also present as a raised area with ulceration. Basal-cell cancer grows slowly and can damage the tissue around it, but it is unlikely to spread to distant areas or result in. Morphea or localized scleroderma is a rare disorder with characteristic clinical features. The treatment of this disease involves the use of long term immunomodulators. Learn more about the clinical features, pathophysiology, laboratory diagnosis, treatment, and the prognosis. Learn more about it in our topic Localized scleroderma often termed morphea in dermatology represents autoimmune disorder characterized by skin thickening and increased collagen deposition with deposition of calcium, it usually affects the dermis and subcutaneous tissue, causes fibrosis and atrophic hardening of the skin; however, it can affect the muscle, fascia, tendons.

Pathology Outlines - Lichen sclerosus et atrophicu

Eccrine squamous syringometaplasia in a patient with plaque‐type morphea Eccrine squamous syringometaplasia in a patient with plaque‐type morphea El‐Fidawi, Georges; Akel, Randa; Abbas, Ossama 2014-06-01 00:00:00 To the Editor : Metaplasia is a process in which one differentiated cell type is replaced by another in an adaptive cellular mechanism in response to various stimuli These include: (1) noduloulcerative type (2) the superficial spreading type (3) pigmented (4) Pinkus tumor (5) morphea-like and (6) the cystic type. We herewith report a case of overlap of superficial spreading BCC with morphea-like basal cell carcinoma in a 63 year-old woman for its rarity and unique features In our series, 84 percent of basal cell carcinomas are found on head and 16 percent are found on trunk and extremities. The most common site for occurrence is the nose (25.09%) BCCs can be divided into several subtypes: superficial, nodular, pigmented, morphea like, and basosquamous. Nodular BCC is the most common type Introduction . Nonmelanoma skin cancer (NMSC), is the most common malignancy in humans. The incidence of NMSC is not consistently reported to cancer registries; however, an estimated 5.4 million cases of NMSC were diagnosed in the United States in 2012. 1,2 The average treatment cost of NMSC in the United States from 2007 to 2011 was estimated to be $4.8 billion annually.

Yes and no: Basal cell carcinoma is a type of skin cancer which is not malignant in the sense it will not spread to distant parts of the body and threaten life th Read More. 3 doctors agree. 0. 0 comment. 8. 8 thanks. Send thanks to the doctor Abstract Morphea and lichen sclerosus are inflammatory skin diseases that lead to cutaneous sclerosis, and in a number of patients, significant morbidity. The underlying pathogenesis is a combination of vascular damage, infiltration of T cells that release IL-4, and TGF-β-activated fibroblasts producing altered collagen. Morphea can be subdivided into several subgroups: plaque-type (the most. However, these features may not be apparent in a superficial shave biopsy specimen. Misdiagnosis of MAC as desmoplastic trichoepithelioma, morphea form basal cell carcinoma, eccrine carcinoma with squamous differentiation or even squamous cell carcinoma has been reported in 30%-52% of cases

Basal cell carcinoma is a superficial, slowly growing papule or nodule that derives from certain epidermal cells. Basal cell carcinomas arise from keratinocytes near the basal layer, which are sometimes called basaloid keratinocytes. Metastasis is rare, but local growth can be highly destructive. Diagnosis is by biopsy Pathology: Superficial and deep perivascular and focal predominate lymphocytic dermatitis. No sclerosis. Compatible with inflammatory stage of morphea DDx: erythema chronicum migrans and less likely deep gyrate erythema or tumid lupus erythematosus. If clinically suspicious, suggest LYME and LE serology lab Generalized morphea is the most severe form of localized morphea [5, 6].The following clinical diagnostic criteria for this subtype of morphea must be fulfilled: four or more lesions larger than 3 cm in diameter or involvement of two or more of the seven body areas (the head and neck, the right and left upper extremities, the anterior and posterior trunks, and the right and left lower.

Diagnosis. Your doctor may diagnose morphea by examining the affected skin and asking about your signs and symptoms. Your doctor might also take a small sample of your skin (skin biopsy) for examination in a laboratory. This can reveal changes in your skin, such as thickening of a protein (collagen) in the second layer of skin (dermis) Circumscribed superficial morphea is the most common subtype in adults and generally causes few problems besides local discomfort and visible disfigurement. Circumscribed Deep Morphea. In circumscribed deep morphea (morphea profunda), sclerosis reaching into the subcutis is present and may extend into the fascia and muscle. Pathology of. Background Deep Variant Morphea (DMV), previously known as morphea profunda, is an exceptionally rare form of sclerosis that is confined to the skin, and unlike scleroderma, has no systemic or internal organ involvement. The inflammation and sclerosis involves layers of the deep dermis, panniculus, fascia or even the underlying superficial muscle. An initial inflammatory phase, which can be. Morphea of the breast: case reports and review of literature. Breast J 2007;13(3):302-304. Crossref, Medline, Google Scholar; 42 Clark CJ, Wechter D. Morphea of the breast: an uncommon cause of breast erythema. Am J Surg 2010;200(1):173-176. Crossref, Medline, Google Scholar; 43 Seale M, Koh W, Henderson M, Drummond R, Cawson J

Many variants: solid (nodular), superficial multicentric, cystic (cavities are caused by focal degeneration), adenoid, pigmented, invasive, morphea-like with sclerosis and infiltrative growth. The peritumorus slits, basophilia and palisading are usually not present in invasive variants Welcome to Ed's Pathology Notes, placed here originally for the convenience of medical students at my school. as a cause of skin changes, morphea, and intractable ulcers (Arch. Derm. 143: 637, 2007). NORMAL AGING superficial spreading melanoma, vertical growth phase superficial spreading melanoma, gross. This is because the sclerosis of morphea may extend into the subcutaneous fat and superficial fascia (referred to as subcutaneous morphea, morphea profunda, and pansclerotic morphea), and the pathology of fasciitis may extend into the over- lying fat and reticular dermis (some refer to this latter presentation as fasciitis with overlying morphea) According to one study, pathology residencies averaged 216.5 h (~9 days) of dermatopathology training over the course of four years, with an average of only 54.1 h per year of training . Not. Morphea limited to the superficial reticular dermis: Morphea and its variants and the floating sign: an additional finding in morphea. Comparison of the pathology of fascia in eosinophilic myalgia syndrome patients and idiopathic eosinophilic fasciitis

Superficial morphea - ScienceDirec

The rope sign is a dramatic finding presenting as a linear to curvilinear cords (cordonifom) on the lateral chest. It was originally described as an uncommon, but specific feature of Interstitial Granulomatous Dermatitis with Arthritis (IGDA), and has been considered pathognomonic for that disorder. That perspective is no longer tenable Circumscribed superficial (plaque morphea) and generalized morphea are common in adult-onset morphea , while linear scleroderma, both linear trunk/extremity and linear head subtypes, is more common in childhood-onset morphea (10, 11). To achieve personalized management schemes, these factors shall be taken into account Start studying Pathology - terminology. Learn vocabulary, terms, and more with flashcards, games, and other study tools. - collection of neutrophils in the stratum corneum or superficial epidermis, seen in psoriasis. nuclear molding - Decreased staining in morphea

Pathology Outlines - Gyrate erythema

Morphea is an inflammatory disorder that produces sclerosis of the skin and subcutaneous tissues. Disease activity (inflammation) is difficult to determine when pathology extends into the subcutaneous fat. Because deep lesions produce the most devastating permanent sequelae including limb length discrepancy and joint contracture, the lack of measures to discern activity presents a substantial. Normal Anatomy of the Breast Skin. The breast is a modified cutaneous exocrine gland composed of skin, subcutaneous tissue, breast parenchyma, and breast stroma ().Linking the upper chest wall, lower abdomen, and axilla, the skin of the adult breast is generally located between the second and seventh intercostal spaces and consists of epidermal, dermal, and hypodermal layers ()

Alterations in collagen and elastin | Plastic Surgery Key

Morphea profunda - Libre Patholog

  1. Morphea is a skin condition that involves a patch or patches of discolored or hardened skin on the face, neck, hands, torso, or feet. The condition is rare and thought to affect less than 3 out of.
  2. imal skin thickening and resolving with hyperpigmentation and mild skin.
  3. Morphea is a localized type of Scleroderma that is characterized by thickened skin patches, which can increase and decrease in size. Generalized Morphea, and Superficial Morphea. The healthcare provider can assist in identifying the type of Morphea an individual is diagnosed with Journal of cutaneous pathology, 37(5), 571-577
  4. Morpheaform basal cell carcinoma (BCC), also called as sclerosing BCC is a rare variant of basal cell carcinoma with more aggressive characteristics and atypical clinical presentation. The vast majority of basal cell carcinomas are nodular or superficial. Morpheaform basal cell carcinoma is considered a potentially more aggressive subtype
  5. The propensity to develop multiple BCCs may be inherited. Included among heritable conditions predisposing to the development of this epithelial cancer are nevoid basal call carcinoma syndrome or basal cell nevus syndrome (BCNS), Bazex syndrome, 15 and Rombo syndrome. Patients with BCNS may develop hundreds of BCCs and may exhibit a broad nasal root, borderline intelligence, jaw cysts, palmar.
  6. Weibel (2012) stated that localized scleroderma or morphea is a sclerosing connective tissue disease of the skin, which may affect underlying tissues such as subcutis, muscle and bone. Many patients show extra-cutaneous symptoms and anti-nuclear antibodies, however, secondary transformation into systemic sclerosis does not occur

Morphea - an overview ScienceDirect Topic

Morphea Limited to the Superficial Reticular Dermis: An

  1. Superficial basal cell carcinoma is the second most common type of BCC, accounting for around 15% of cases. As per its name, superficial BCC is characterized by a flat, distinct area of discoloration, referred to as a macule. It is usually pink-to-red in color with well-defined edges and a scaly appearance
  2. Typical lipomembranous fat necrosis was also observed in eight cases (21%) of erythema nodosum, three (8%) of morphea or subcutaneous morphea (or both), two (5%) of lupus panniculitis, two (5%) of necrobiosis lipoidica, and in single cases of polyarteritis nodosa, necrotizing vasculitis, and erysipelas
  3. Superficial morphea (SM) is an uncommon entity that is characterized by localized deposition of extra collagen in the papillary and upper reticular dermis. Although there are few reports describing the clinical and pathological features of this variant, there is a debate about its relation to other atrophodermic diseases [ 3 ]

How are the lesions of the superficial variant of

Skin is the largest organ in the body. In a 70-kg individual, the skin weighs over 5 kg and covers a surface area approaching 2 m2. Human skin consists of a stratifi ed, cellular epidermis and an underlying dermis of connective tissue.Beneath the dermis is a layer of subcutaneous fat, which is separated from the rest of the body by a vestigial layer of striated muscle Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not associate Raynaud's phenomena or sclerodactyly, which are encountered in systemic scleroderma 1. Skin of Eyelids Eye Lashes Eyelids pathology Anatomy of Conjunctiva. 2. 1. Epidermis The outer part of the eyelid is lined by cornified stratified squamous epidermis. It is made up of basal cells, melanocytes, Langerhans cells, keratinocytes and on top, the dead cell layer (also known as the stratum corneum) made up of corneocytes

Connective Tissue/Muscle Pathology - Musculoskeletal with

Elastic fiber pattern in scleroderma/morphea - Walters

Pathology - S2B4 - Skin 3 Flashcards - Cram

Morphea with discoid lupus erythematosus

  1. Lupus profundus is a rare manifestation of cutaneous lupus erythematosus, seen in 1% to 3% of patients. It most commonly presents in association with classic chronic cutaneous lesions of discoid lupus erythematosus; however, such lesions, as well as a clinical history of lupus erythematosus, may be lacking
  2. Basal cell carcinoma (BCC) is a nonmelanocytic skin cancer (ie, an epithelial tumor) that arises from basal cells (ie, small, round cells found in the lower layer of the epidermis). The prognosis for patients with BCC is excellent, but if the disease is allowed to progress, it can cause significant morbidity
  3. Basal cell carcinoma. Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor (s)-in-Chief: Maneesha Nandimandalam, M.B.B.S. [2] Synonyms and Keywords: Basal cell epithelioma, rodent ulcer, Ronald Reagan tumor, infiltrative basal cell carcinoma, basal-cell cancer,Skin Fibroepithelial Basal Cell Carcinoma, Skin Signet Ring Cell.
  4. Atlas of dermatopathology: Localized scleroderma, morphe
  5. Superficial morphea: case report, look-alikes
  6. Histopathologic Spectrum of Morphea : The American Journal